Dipyridamole Discussion

Xdip - to my knowledge, no. But I think that might be a question to Shira - as they would be more aware about any research conducted. Email is given above.

Please let us know if there is!

I'm visiting my eye consultant next week, he'll examine my eyes and tell me if there are any changes. I'll report any comments back here.

Claire

Your advice is absolutely invaluable! Would love to see your before and after photos When you administer your drops, do you block your tear duct? And were you ever woken up by the dryness of your eyes in the night prior to taking the drops - this is something that's slowly improving for me now.

I tried Omega 7 for 2.5 months but haven't seen a marked improvement to justify the cost of them. I use cold compresses in sterile cucumber water which helps on the comfort front, but I'm keen not to dilute the concentration of the drops in the eye so I tend to space things apart a bit.

Hi!

No I don't block my tear ducts (I imagine that's be tricking to do while applying the drops!) but when I administer them I close my eyes immediately after putting them in, and for about 2 - 3 minutes, with my eyes closed, I roll my eyes to ensure the drops spread everywhere. Sounds strange I know!

I did have a few sleepless nights due to how dry and raw my eyes felt, but thankfully I no longer suffer from that.

If you PM me your email address I'll send some over. For some reason I cannot post them on here, it just won't accept them.

Hi
Just started using the dipyridamole drops twice a day.
Have dry eyes, red veins and pings.
No improvements as yet!!
Just to say Claire has been very helpful with her advice, it's great to talk to someone in the same position.
Hopefully these drops are a way forward.

I was hoping Rebecca unlock topic. But she's not manifested, so let's go.

Suzy. I used approximately 7 drops per day. While I used the eyedrops the eye irritated a little bit, getting noticeably redder. But after I stop using, felt that there was an improvement in appearance. Nothing miraculous. But improved.

I think you're wearing very little. I used 7 drops for 1 month approximately.

Someone asked about side effects from prolonged use.
I think that there is no scientific answer to that yet.
Not even the developer possess double-blind studies about it.
So I believe that we should be aware that we are our own guinea pigs.

Andre - really glad to hear the drops have taken some effect. It's a real shame we can't continue the old thread but good that we can least discuss it on here.

How long are you planning to use the drops for? And how has your eyes improved? Reduction of veins or just a decrease in the redness?

Claire, i bought four more drops. I plan use seven drop per day for two months. After this, i plan use three drops per day, one in the morning and two before i sleep.

It helped me with redness and morning pain (and morning redness too).

Is dificult to explain how it helped with the redness.
I think the inflammation is de cause of my redness.
As my tears dont give a effective protection for my cornea, the agression suffered during the day (wind, dust, air conditioner, etc) cause inflammation and redness.
I think the drops helps to decrease inflamatory response. Consequently, i have less redness (and pain too).

To explain how i see redness decrease.
When your eyes are very inflamed you have more redness and more veins.
With less inflamation, the eyes get more white and some veins disapear.
This is what i feel with the drops.

As my eyes continue without protection, this sensation varies accord with the air humidity of day. However, i feel my eyes are better.

It help me a lot with morning redness and pain.
Until now, everything i use to sleep dont help me in the morning.
Preservative-free drops worsened my eyes. Saline help if my eyes is not very inflamed. Autologous serum drops have helped me a lot. But i have to use this one hour before i sleep.

With the Dipy (i will call the drops with this name - Dipy - Is more easy to type) i found a great combination. I use the autologous serum drops during whole day and DIPY before sleep and after waking up.

This way my eyes feel better in the morning. This is the unique substance that not bothering my eyes during the night. And i wake up with fresh eyes sensation. With no sand sensation on eyes.

This is the good part.

In the beggining it was not so easy.
In the first day my eyes were red and swollen.
I continued using the drops. (by my own risk)
In the second week, the eyes were less red. And i felt less burning and "sand sensation".
After one month of use, i saw the improvements.
In the last two days, the bottle was with little quantity of drops. Then i used this only at the night, before sleep, and at morning, after wake up. In this way i discovered the combination that i said above.

This is a little of my history with Dipy.
In this moment i am in dallas, but this is another history.

Ps1: I have used seven drops per day because it have fifteen days until expire after you open the bottle. And this way, you will reach the same substance quantity used in a mini-research that i read.

Ps2: I have Dryeyes due the lasik surgery. In addition to the methods that i have told in this post, i use other tools for my dry-eyes,

Ps3: I Always have a doctor that accompanies my "experiences".

Ps4: I am sleepy and i did not do the text revision.

Hi Andre!

Thanks for your informative reply. My eyes got worse from using other drops too, even preservative free ones. I was at wits end until I tried the dipyridamole drops! I hope the redness keeps on getting better for you.

Ok, just had my appointment with my eye consultant to check the health of my eyes since using the drops. I've come back all clear and he's even discharged me! My eye pressure is fine, my tear film/glands are in working order, he even noted the inflammation has died down and my eyes don't look inflamed anymore. Big relief! I only told him what I was using after he gave me an overall summary of how things were looking. He said he never heard of using dipyridamole before but will research into it. He said it looks like it's helping but couldn't make any further comment on it (for professional reasons I imagine).

So good news from me!

I am soo happy to have found this forum!

I am a 26 year old male, I have been suffering from severely inflamed pinguecula's in both eyes for 5 years now

Andrea and Claire, thank you soo much for posting the information you have so far.

Claire congratulations on your eye health check up yesterday, I was very happy to hear that.

I am very anxious to order these eye drops, but nervous about us being the "guinea pigs" with these drops...short term, long term possible complications....ugh.

Everyone please continue to update and share your progress with these eye drops. I can't believe these actually might be the miracle drops I've been searching for for the last 5 years.

Claire,

Thank you so much for the pictures. Your eyes look great. There to the point were they look really white. And congrats on the good news about your eye doctor visit. This is exciting for everyone. We're all cheering for you and thanks for sharing invaluable information. Would you say your eyes are almost to the point where you might stop all eye drops except for maybe tears?

IIAwarenessII - nice to hear from you. I'm sorry to hear about your pingucelas. Admittedly, I was petrified when I first start using the drops as my tear film was so inflamed I was worried about making things worse. I would never push someone to use these drops unless they were completely comfortable in doing so and even then, I'd warn, it does take a while to see the results. It tore me into shreds waiting week after week to see whether they'd work or get worse, I feel fortunate to be in this position to say they are helping.

Admin - thank you! I'm such a perfectionist that - although they look so much better than they once did - I want to keep going until they look more how they did before the inflammation as there are still a few pesky veins left which was caused by the irritation. It sounds very petty but when you're so hung up on the appearance of your eyes - like I've been the past year - you want to make them look the best that they can. I see the trial lady used it up to a year in MedInSights report so I may - now knowing medically I'm in the clear - keep on going with them for another month or two and hope it keeps on getting better.

For those reading these posts that have begun their journey with the drops please report your feedback on here! It is so helpful to others, whether it is good, bad or in between! I think it's so important to share our experiences in order to help/comfort/inform others and we need to hear from other users (as I'm sure people are getting sick of hearing from me!) so get in touch! X

Hi everyone,

My issues are so similar to many of yours.  In my mid 20s and started to develop a ping and now a few years later despite following doctor's instructions have four, with the original one constantly very red and irritated.  A specialist diagnosed me with MGD and advised me there wasn't much that could be done other than surgery in the future.  Anyway, I'm terribly self conscious about it and it's negatively affecting my career and social life.

I started using the drops 3 weeks ago and haven't seen much of an esthetic change at all, but have noticed slightly less dryness feeling throughout the day.  I will say that I was using them 5 times a day very regularly until a few days ago - due to a busy schedule and a bit of frustration at not seeing results.  

I'm really happy to have found this forum so that we can all share our progress.  Is it possible to get pictures from some of you showing the change?  These drops are not cheap and I need some motivation to stick with it!  

Thanks in advance!

Hi

Hopefully this image link will work.

https://i.servimg.com/u/f19/19/21/54/07/image17.jpg

That's the before/after with my eyes. Unfortunately that's the only 'before' picture I have, so I do appreciate the lighting is different but that's all I have to compare them to!

Mimi - it does take a while to see improvements. I know patience is really a virtue in this scenerio as I completely understand what it's like to have a career/social life affected by this. The fact they are getting less dry is a good thing.

Claire,

Thank you so much for the photos! I'm so happy you've had such great results - that's a pretty drastic difference. You've helped to keep me hoping. Do you mind if I ask how long it took before you saw those changes?

Hi Mimi.

You're welcome! I've been using the drops for nearly 5 months now. I took the 'after' pic the other day.

Thank you for the picture Claire, great progress!

I just ordered the drops yesterday. I will report back regularly with before and after pictures.

Hi everyone,

I just read a post on the Dry eye forum from a user called Fitch.

See below:

just wanted to let everyone know i had a terrible experience with the dipyridamole drops and i have already communicated it to Shira at MedInsight. I was in the process of improving with my corneal neuralgia in January of this year. I used the dipyridamole drops from buyldn.com for the month of February and it set me back taking my pain from a 6 to a 9 or 10. It is now 3 months later and i still have not gotten back to where i was in January and still have pain of 9 or 10 in my eyes. My MD thinks the drops set off my corneal nerves. I highly regret using the drops and i am out $120 as well which only adds insult to injury (literally) I wish i had never seen the thread on dryeyezone so i am glad you are moderating it now. With all respect to ClaireW I highly regret using these drops and would caution anyone who wants to try them to do your homework first. I did my homework and even had the blessing of my eye MD and still wound up hurting myself unfortunately.

I'm posting this because A) I don't want this forum to be solely about my positive experiences. reactions to this drop can range dramatically, I don't want to create any false impression that it will work for everyone. In fact, as we can see here, it's had the opposite effect. B) to remind you to exercise the upmost caution if you do chose to use these. As I said taking them is at your risk but I would advise consulting a doctor first or at least making an opthmologist aware that you are using them. The difficult thing is that the drops, as a vasodilator, naturally causes some irritation and redness on application to the eye, which does go away but it'll be harder to pinpoint whether you are having a bad reaction to then or not. If you feel any pain which is more than a slight stinging when using a drop I would immediately stop and inform Shira. c) with any new drug or medicine there is always going to be people who react well and people who might end up suffering more. It's a heavy gamble so just be aware of all the info out there and report back here if there's anything we need to be aware of. I don't want to be seen as a one woman band promoting anything that could be potentially harmful just because I had a positive experience. Just be careful!

We appreciate you posting this negative review Claire, as all feedback is important.
However, Mr. Fitch intended to cure his condition of "corneal neuralgia" with these eye drops. Nowhere in the patent or case studies of the dipyridamole eye drops does it mention corneal neuralgia.

All of us thus far on this forum have a similar condition, pinguecula's, inflamation, pterygium, neovascularization, redness, chronic dry eye.....and this is what the dipyridamole eye drops have been intended to be used for.

Mr. Fitch's condition of "corneal neuralgia" is a completely separate eye condition.

Hi,

I guess I felt partly responsible as I was leading on the thread and now he's suffering! Just want people to be aware of all the possible side effects. I very much hope that fitch's experience is one bad exception in a sea of positive stories - but just thought it'd be wise to share.

I definitely understand and it was important to share. Once again, we appreciate you posting this negative review Claire, as all feedback is important about these eye drops.

My intent was just to inform guests of the condition Mr. Fitch was attempting to cure (corneal neuralgia) with these drops, in contrast to the condition most of us on this forum suffer from (pinguecula's, inflamation, pterygium, neovascularization, redness, chronic dry eye.)

I'm sorry for FItch. It's terrible to walk back.
It's a warning to all who will test these drops.
Remember that this is a tool not widely tested.
Make sure it has gone all the way to contain your inflammation.
Have clear goals and read all the posted material on the subject before.
And when you decide to use, be fully aware that you are going on your own.

I would like to make a chart, like a pyramid (or otherwise), showing which are the tools available for those who have dry eye and link tools with topics that discuss the matter. In this graph, the drops would be in the upper portions, one of the last tool to be tested. Maybe open a topic for all help.
I think that could help newcomers avoid falling into traps, using advanced tools before trying the basics.
What do you think, Claire?

Hi Andre,

It's a good idea - not sure how to put it into practice in here. You will need to speak to the creator of this forum (user Admin).

Hello everyone!
First of all I want to say that I'm very glad I've come across this forum! It's so cool we can share our impressions on dipyridamole eye drops with each other!
Secondly: ClaireW, you've got great results, it's really  amazing Other few months and, hopefully, your eyes will be all clear!
As for me, I'm going to finish the second bottle of the drops. I mean I've been using the drops for about 4 weeks. I can't say I see some visual changes in my eyes but what I'm sure of is that I don't feel any discomfort or dryness anymore. So, I hope, the drops are working for me!

Hi Ayza, I'm glad to hear your eyes are feeling less dry, just wondering how many drops you are applying?

I'm using 3 drops per day, I can't see any visual results but my eyes are definetly less dry, this could be due to the drops or I've just started using diluted tea tree foaming wash!! But hopefully this feeling continues. So nice to wake up and have fresher eyes that usually continues throughout the day. Please may it last.